Cardiothoracic & vascular anesthesia

Postoperative Pain Intensity After Single-port, Double-port, and Triple-port Video-assisted Lung Lobectomy: A Three-arm Parallel Randomized Clinical Trial

J Cardiothorac Vasc AnesthPublished Randomised controlled trial

Authors' conclusion

This study revealed no differences in pain intensity in the early postoperative period between three different technical variants of VATS lobectomy when an analgesia protocol based on thoracic epidural anesthesia was used.

Study context

Population
Adults, ASA I–III, scheduled for elective video-assisted thoracic surgery (VATS) lobectomy for early-stage non-small cell lung cancer, under multimodal analgesia incl. thoracic epidural analgesia91 completed protocol
Participants
112 adults
Comparison
Single-port vs double-port vs triple-port VATS lobectomy
Primary endpoint
Postoperative pain intensity at rest and when coughing
Follow-up
First 72 hours after surgery
Methodological detailsprospective, three parallel arms, single-centre
  • Prospective
  • Three parallel arms
  • Single-centre

Primary result

As reported in the abstract

Postoperative pain intensity · first 72 hours
No significant difference between groups in pain at rest
p = 0.319
No significant difference between groups in pain when coughing
p = 0.202

Safety

Postoperative complications

No difference in incidence between groups

Original publication

Postoperative Pain Intensity After Single-port, Double-port, and Triple-port Video-assisted Lung Lobectomy: A Three-arm Parallel Randomized Clinical Trial. J Cardiothorac Vasc Anesth. Published 7 March 2025. doi:10.1053/j.jvca.2025.02.051

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