Perioperative medicine & outcomes
Prevalence and Incidence of Oral Benzodiazepine Use in Hospitalized Surgical Patients: A Retrospective Cohort Study
Authors' conclusion
In this study, one-fifth of patients admitted to surgical departments were administered oral benzodiazepines for sleep disturbances and anxiety.
Study context
- Population
- Adult surgical patients admitted to a university hospital in Rotterdam, The Netherlands, September 2018–September 2022
- Participants
- 10,896 patients · 14,928 admissions
- Outcome
- Prevalence and incidence of oral benzodiazepine use during hospitalization
Methodological detailssingle-centre, routinely collected health care data
- Single-centre
- Routinely collected health care data
Main finding
As reported in the abstract
Prevalence of benzodiazepine administrations
Prevalence of benzodiazepine administrations (of 14,928 admissions)
21.6%
Observational data: associations, not effects.
Further findings
| Outcome | aOR | |
|---|---|---|
| Benzodiazepine administration, female vs male | 1.09 (95% CI 1.002–1.19) | |
| 30-day surgical readmission, benzodiazepine administration vs none | 1.37 (CI 1.22–1.54) | |
| 0.512Adjusted odds ratio (log scale) |
Number of tablets given during hospital stay
- Median number of tablets (IQR not named; 1-7)
- 3
Most prescribed agents
- Temazepam
- 33%
- Oxazepam
- 24%
- Zopiclone
- 19%
Original publication
Prevalence and Incidence of Oral Benzodiazepine Use in Hospitalized Surgical Patients: A Retrospective Cohort Study. Ann Surg. Published 30 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →