Prevalence and risk factors for chronic postamputation pain requiring analgesia or nerve interventions: a population-based study in East Asia
Authors' conclusion
The prevalence of PAP requiring subsequent analgesia or nerve interventions in this East Asian population is 18.1%. Identified risk factors include multiple medical comorbidities and pre-existing radiculopathy or myelopathy.
Study context
- Population
- East Asian individuals who underwent surgical amputation, Taiwan Longitudinal Health Insurance Database, 2000–2019
- Participants
- 7,287 amputees
- Outcome
- Prevalence of chronic PAP requiring subsequent analgesia or nerve interventions
Methodological detailsclaims database, multivariable regression
- Claims database
- Multivariable regression
Main finding
As reported in the abstract
PAP requiring intervention (prevalence)
- Prevalence of postamputation pain (PAP) requiring intervention: 18.1% (95% CI 17.2%, 19.0%); 1318 patients
Observational data: associations, not effects.
Further findings
Risk factors for PAP (multivariable regression)
| OR (95% CI) | ||
|---|---|---|
| Cancer | 2.20 (1.27–3.68) | |
| Peripheral artery disease | 2.11 (1.66–2.69) | |
| Infection | 1.93 (1.55–2.40) | |
| DM | 1.85 (1.45–2.37) | |
| Higher Elixhauser Comorbidity Index | 1.04 (1.02–1.06) | |
| Prior radiculopathy | 1.30 (1.13–1.51) | |
| Myelopathy | 1.33 (1.14–1.55) | |
| AgeSlight inverse association | 0.99 (0.98–0.99) | |
| 0.20.5125Odds ratio (log scale) |
Original publication
Prevalence and risk factors for chronic postamputation pain requiring analgesia or nerve interventions: a population-based study in East Asia. Reg Anesth Pain Med. Published 20 November 2024. doi:10.
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