Airway management

Prevalence and risk factors of difficult mask ventilation: A systematic review and meta-analysis

J Clin AnesthPublished Systematic review and meta-analysis of observational studies

Authors' conclusion

Our results demonstrated the strengths of 13 most common risk factors for predicting difficult MV, which may serve as an evidence-based reference for clinicians to incorporate into their daily practice.

Study context

Population
Adults receiving anesthetic induction requiring mask ventilation, operating room
Participants
335,846 adults · 20 observational studies
Outcome
Commonly reported risk factors for difficult mask ventilation and comparison of their predictive strengths
Methodological detailsEMBASE, MEDLINE, Google Scholar and Cochrane Library searched from inception to July 2022
  • EMBASE, MEDLINE, Google Scholar and Cochrane Library searched from inception to July 2022

Pooled result

As reported in the abstract

Risk factors for difficult mask ventilation (all p < 0.05)
Neck radiation, OR (5 studies, n = 277,843)
5.0
Increased neck circumference, OR (11 studies, n = 247,871)
4.04
Obstructive sleep apnea (OSA), OR (12 studies, n = 331,255)
3.61
Presence of beard, OR (12 studies, n = 295,443)
3.35
Snoring, OR (14 studies, n = 296,105)
3.06
Obesity, OR (11 studies, n = 278,297)
2.99
Male gender, OR (16 studies, n = 320,512)
2.76
Mallampati score III-IV, OR (17 studies, n = 335,016)
2.36
Limited mouth opening, OR (6 studies, n = 291,795)
2.18
Edentulous, OR (11 studies, n = 249,821)
2.12
Short thyroid-mental distance, OR (6 studies, n = 328,311)
2.12
Old age, OR (11 studies, n = 278,750)
2
Limited neck movement, OR (9 studies, n = 155,101)
1.98

Further pooled results

Prevalence of difficult mask ventilation, general population

Prevalence (16 studies, n = 334,694)
6.1%

Prevalence of difficult mask ventilation, obesity

Prevalence (4 studies, n = 1152)
14.4%

Original publication

Prevalence and risk factors of difficult mask ventilation: A systematic review and meta-analysis. J Clin Anesth. Published 4 July 2023. doi:10.1016/j.jclinane.2023.111197

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