Airway management

Video Laryngoscopy vs Direct Laryngoscopy for Endotracheal Intubation in the Operating Room: A Cluster Randomized Clinical Trial

JAMAPublished Randomised controlled trial

Primary result · More than 1 intubation attemptResult — go to the resultProportional OR for number of intubation attempts 0.20 95% CI 0.14–0.28

Authors' conclusion

In this study among adults having surgical procedures who required single-lumen endotracheal intubation for general anesthesia, hyperangulated video laryngoscopy decreased the number of attempts needed to achieve endotracheal intubation compared with direct laryngoscopy at a single academic medical center in the US.

Study context

Population
Adults ≥18 y having elective or emergent cardiac, thoracic or vascular surgery requiring single-lumen endotracheal intubation for GA, single US academic hospital
Participants
7,736 adults · 8,429 surgical procedures
Comparison
Video laryngoscopy vs Direct laryngoscopy
  • Video laryngoscopyn = 4,413
  • Direct laryngoscopyn = 4,016reference
Primary endpoint
Number of OR intubation attempts per surgical procedure
Methodological detailscluster randomized, multiple crossover, single-centre
  • Cluster randomized
  • Multiple crossover
  • Single-centre

Primary result

More than 1 intubation attempt

Proportional OR for number of intubation attempts

0.20

95% CI 0.14–0.28

P < 0.001

Events by treatment group

Video laryngoscopy vs Direct laryngoscopy
proportional OR for number of intubation attempts 0.20 (95% CI 0.14–0.28); P < 0.001

As reported in the abstract

Secondary outcomes

OutcomeVideo laryngoscopyDirect laryngoscopyRR (95% CI)P value
Intubation failure (switch to alternative device or >3 attempts)0.27%4.0%0.06 (0.03–0.14)P < 0.001
OutcomeUnadjusted absolute risk difference (95% CI)
Intubation failure (switch to alternative device or >3 attempts)−3.7% (−4.4% to −3.2%)

Safety

Composite of airway and dental injuries

Composite of airway and dental injuries

Did not differ significantly

Original publication

Video Laryngoscopy vs Direct Laryngoscopy for Endotracheal Intubation in the Operating Room: A Cluster Randomized Clinical Trial. JAMA. Published 16 April 2024. doi:10.1001/jama.2024.0762

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