Pediatric anesthesia & critical care

Video laryngoscopy vs. direct laryngoscopy in infants and neonates: A systematic review and meta-analysis

J Clin AnesthPublished Systematic review and meta-analysis of randomised trials

Pooled result · First-attempt success rateResult — go to the resultOR for first-attempt success 2.13

Authors' conclusion

This meta-analysis suggests that VL may improve first-attempt success and glottic visualization and may reduce complications compared with DL in infants and neonates.

Study context

Population
Infants <1 year old and neonates (0–28 days old) undergoing endotracheal intubation
Participants
1,918 infants · 17 randomized controlled trials (RCTs)
Comparison
Video laryngoscopy (VL) vs direct laryngoscopy (DL)
Outcome
First-attempt success rate
Methodological detailssubgroup analysis for neonates
  • Subgroup analysis for neonates

Pooled result

As reported in the abstract

OR for first-attempt success

2.13

P < 0.001

By group

Further pooled results

First-attempt success rate, neonates (subgroup)

OR for first-attempt success 2.12 · P = 0.027

OutcomeMDP value
Time to best view−2.85P < 0.01
POGO scores16.8P < 0.01
Time to intubation (TTI)No advantage of VL over DL0.79P = 0.49

Safety

Complications

OR 0.33 · P = 0.022

Original publication

Video laryngoscopy vs. direct laryngoscopy in infants and neonates: A systematic review and meta-analysis. J Clin Anesth. Published 25 September 2025. doi:10.1016/j.jclinane.2025.112024

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