Perioperative medicine & outcomes
Prevalence of frailty and association with patient centered outcomes: A prospective registry-embedded cohort study from India
Main finding · ICU mortalityResult — go to the resultAdjusted odds ratio 2.04 95% CI 1.25,3.33Authors' conclusion
Frailty is common among critically ill patients in India and is associated with worse outcomes.
Study context
- Population
- Adult ICU patients in India anticipated to stay at least 48 h
- Participants
- 838 patients · 7 intensive care units (ICUs)
- Exposure
- Frailty vs no frailty
- Outcome
- ICU mortality
Methodological detailsmulticentre (7 ICUs)
- Multicentre (7 ICUs)
Main finding
As reported in the abstract
Adjusted odds ratio
2.04
95% CI 1.25,3.33
Frail vs Not frail
aOR 2.04 (95% CI 1.25,3.33)
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Estimate | |
|---|---|---|
| Hospital mortalityFrail vs Not frail | aOR 2.36 (95% CI 1.45,3.84) | |
| Stage 2/3 AKIFrail vs Not frail | unadjusted OR 2.35 (95% CI 1.60–3.43) | |
| Receipt of NIVFrail vs Not frail | unadjusted OR 2.68 (95% CI 1.77–4.03) | |
| Receipt of vasopressorsFrail vs Not frail | unadjusted OR 1.47 (95% CI 1.04–2.07) | |
| Receipt of kidney replacement therapyFrail vs Not frail | unadjusted OR 3.15 (95% CI 1.90–5.17) | |
| 0.20.5125Ratio (log scale) |
Prevalence of frailty
- Prevalence of frailty
- 19.8%
Risk factors for frailty
- Charlson comorbidity index, OR
- 1.73 (95% CI 1.39,2.15)
- SGA mild/moderate malnourishment, OR
- 1.90 (95% CI 1.29, 2.80)
- SGA severe malnourishment, OR
- 4.76 (95% CI 2.10,10.77)
Original publication
Prevalence of frailty and association with patient centered outcomes: A prospective registry-embedded cohort study from India. J Crit Care. Published 21 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →