Perioperative medicine & outcomes
The 3-Minute Diagnostic Confusion Assessment Method severity score correlates with the Delirium Rating Scale–Revised–98 and with biomarkers of delirium
Authors' conclusion
The 3D-CAM-S severity scores correlated with DRS, delirium duration, and biomarkers of delirium.
Study context
- Population
- Patients >65 yr undergoing major elective surgery with anticipated hospital stay ≥2 days; excluded dementia, nursing home residents, neurosurgery, unable to complete neurocognitive testing204 completed both assessments
- Participants
- 226 patients
- Exposure
- 3D-CAM severity scores vs DRS severity scores
- Outcome
- Correlation of peak 3D-CAM-S scores with peak DRS severity scores
Methodological detailspaired assessments
- Paired assessments
Main finding
As reported in the abstract
Peak 3D-CAM-S vs peak DRS severity
Correlation, raw score (ρ)
0.74
P<0.001
Correlation, short form (ρ)
0.66
P<0.001
Observational data: associations, not effects.
Further findings
Peak 3D-CAM-S raw score vs delirium duration and severity duration AUC
- Delirium duration (ρ)
- 0.71, P<0.001
- Severity duration AUC (ρ)
- 0.91, P<0.001
3D-CAM-S raw score vs biomarkers of delirium
- Worse Trail Making Test B (ρ), n=177
- 0.37, P<0.001
- Slow-wave EEG power (ρ), n=73
- 0.3, P=0.001
- Plasma neurofilament light (ρ), n=61
- 0.26, P<0.05
- Plasma tau (ρ), n=63
- 0.41, P<0.001
Original publication
The 3-Minute Diagnostic Confusion Assessment Method severity score correlates with the Delirium Rating Scale–Revised–98 and with biomarkers of delirium. BJA Open. Published 21 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →