Perioperative medicine & outcomes
Prevalence of postoperative neurocognitive disorders in older non-cardiac surgical patients: A systematic review and meta-analysis
Authors' conclusion
The overall prevalence of POCD in older non-cardiac surgical populations was 23 %, 16 %, 10 %, and 3 % at day 7, 1 month, 3 months, and 1 year, respectively. Abdominal surgery had a higher prevalence of POCD than orthopedic surgery.
Study context
- Population
- Non-cardiac surgical patients aged ≥60 years
- Participants
- 12,921 patients · 39 studies
- Outcome
- Prevalence of POCD
Methodological detailsmeta-regression
- Meta-regression
Pooled result
As reported in the abstract
Overall prevalence of POCD
Day 7
23 %
95 % CI: 20 %, 27 %
1 month
16 %
95 % CI: 7 %, 25 %
3 months
10 %
95 % CI: 8 %, 13 %
1 year
3 %
95 % CI: 2 %, 4 %
Further pooled results
| Outcome | β (95 % CI) | P value |
|---|---|---|
| POCD prevalence, abdominal vs orthopedic surgery (meta-regression) · day 7 | 0.13 (0.03–0.22) | P = 0.01 |
| POCD prevalence, abdominal vs orthopedic surgery (meta-regression) · 3 months | 0.49 (0.40–0.58) | P < 0.001 |
Original publication
Prevalence of postoperative neurocognitive disorders in older non-cardiac surgical patients: A systematic review and meta-analysis. J Clin Anesth. Published 7 April 2025. doi:10.
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