Prevalence of preoperative metabolic disturbances in elderly patients with hip fracture and their association with mortality – A retrospective cohort study
Authors' conclusion
Preoperative acidosis and lactatemia are common among patients ≥65 years having hip fracture surgery and are associated with 90-day all-cause mortality. Time from hospital admission to surgery is not an independent risk factor, once adjusted for metabolic indices.
Study context
- Population
- Patients ≥65 years having first traumatic hip fracture surgery, single tertiary centre, 2018–20211,227 in multivariable analyses
- Participants
- 1,267 patients
- Exposure
- Preoperative acidosis and lactatemia vs neither
- Outcome
- 90-day mortality
- Follow-up
- 90-day
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Each group vs neitherAdjusted odds ratio (95% CI)P value
Acidosis
1.99(1.31–3.04)
P = 0.001Lactatemia
2.32(1.44–3.74)
P = 0.001- All-cause 90-day mortality rate (N = 114)
- 9%
Observational data: associations, not effects.
Further findings
Time from hospitalization to surgery and mortality
| aOR (95% CI) | ||
|---|---|---|
| Time from hospitalization to surgeryAdjusted for metabolic indices | 1.00 (0.99–1.00) | |
| 0.512Adjusted odds ratio (log scale) |
- Time from hospitalization to surgery and mortality — Median [IQR] time from hospitalization to surgery (hours)
- 28 [20, 42]
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Prevalence of preoperative metabolic disturbances in elderly patients with hip fracture and their association with mortality – A retrospective cohort study. J Clin Anesth. Published 12 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →