Prognostic evaluation of quick sequential organ failure assessment score in ICU patients with sepsis across different income settings
Primary result · 28-day mortality with higher qSOFAResult — go to the resultAdjusted relative risk 1.09 CI 1.00–1.18Authors' conclusion
qSOFA was independently associated with 28-day mortality in ICU patients admitted for sepsis. In LLMIC and UMIC countries/regions, qSOFA was associated with early to late mortality but only early mortality in HIC countries/regions.
Study context
- Population
- ICU patients admitted for sepsis in Asian ICUs
- Participants
- 4,826 patients · 343 ICUs · 22 countries
- Comparison
- Quick sequential organ failure assessment (qSOFA) score at ICU admission and mortality
- Primary endpoint
- Association between qSOFA and 28-day mortality
- Follow-up
- 28 days
Methodological detailsinternational, multicentre
- International
- Multicentre
Primary result
28-day mortality with higher qSOFA
Adjusted relative risk
1.09
CI 1.00–1.18
P = 0.038
qSOFA
adjusted RR 1.09 (CI 1.00–1.18); P = 0.038
As reported in the abstract
- Higher qSOFA associated with increasing 28-day mortality in low and lower middle income (LLMIC)
- P < 0.001
- Higher qSOFA associated with increasing 28-day mortality in upper middle income (UMIC)
- P < 0.001
- No association of qSOFA with 28-day mortality in high income (HIC)
- P = 0.220
Further findings
90-day mortality
- Higher 90-day mortality with increased qSOFA in LLMIC
- P < 0.001
- Higher 90-day mortality with increased qSOFA in UMIC
- P < 0.001
- Association in LLMIC and UMIC only, not HIC
3-day mortality
- Higher 3-day mortality with increasing qSOFA across all income countries/regions
- P < 0.001
Original publication
Prognostic evaluation of quick sequential organ failure assessment score in ICU patients with sepsis across different income settings. Crit Care. Published 23 January 2024. doi:10.
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