Pediatric anesthesia & critical care
Prognostic Value of Leuko-glycemic Index as a Marker of Immediate Postoperative Events After Repair of Complete Atrioventricular Septal Defect in Infants With Down Syndrome
Authors' conclusion
The LGI, a cost-effective and easily measured index, could be a valuable prognostic tool to stratify children with Down syndrome in the immediate postoperative period after complete atrioventricular septal defect correction.
Study context
- Population
- Infants with Down syndrome and complete atrioventricular septal defect undergoing primary intracardiac repair104 analysed
- Participants
- 110 infants
- Outcome
- Postoperative LGI for prolonged mechanical ventilation
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Correlation between postoperative leuko-glycemic index (LGI) and prolonged mechanical ventilation
- p = 0.042
- Postoperative LGI cutoff
- >1,640.16
- AUC
- 0.659 (95% CI 0.548-0.771)
- Sensitivity
- 47.50%
- Specificity
- 81.25%
- P
- p = 0.005
Observational data: associations, not effects.
Further findings
LGI for renal failure
- LGI cutoff
- >2,657.88
- AUC
- 0.723
- P
- P = 0.019
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Prognostic Value of Leuko-glycemic Index as a Marker of Immediate Postoperative Events After Repair of Complete Atrioventricular Septal Defect in Infants With Down Syndrome. J Cardiothorac Vasc Anesth. Published 5 February 2026. doi:10.
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