Cardiac arrest & resuscitation

Prolonged follow-up after apparently unexplained sudden cardiac arrest: A retrospective study

ResuscitationPublished Retrospective cohort study

Authors' conclusion

Our findings emphasized that approximately a quarter of patients who had been initially considered as having apparently USCA after index hospital stay actually reveal heart conditions, especially electrical heart disorders.

Study context

Population
Out-of-hospital cardiac arrest (OHCA) patients admitted alive to a cardiac arrest centre, 2002–2022
Participants
2,482 OHCA patients
Exposure
Unexplained sudden cardiac arrest (USCA) vs electrical heart disorders vs other cardiac etiologies of OHCA
  • USCAn = 68
  • Electrical heart disordersn = 30
Outcome
New diagnoses established during follow-up of USCA survivors
Follow-up
Mean 8.1 ± 6.3 years
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Diagnosis eventually established in USCA patients
GroupValueElectrical heart disorders among new diagnoses
USCA24.3%55.6%, 5/9

USCA

Value24.3%
Electrical heart disorders among new diagnoses55.6%, 5/9

Observational data: associations, not effects.

Further findings

Age

Family history of SCA

OutcomeUSCAElectrical heart disordersOther cardiac etiologies
Lost to follow-up at discharge8.8%20%— not stated in the abstract

— not stated in the abstract

  • Age: p < 0.0001
  • Family history of SCA: p = 0.003

Post-discharge death and appropriate ICD therapy · mean follow-up 8.1 ± 6.3 years

Appropriate ICD therapy delivered
≈10%
No post-discharge death in USCA and electrical heart disorders groups

Original publication

Prolonged follow-up after apparently unexplained sudden cardiac arrest: A retrospective study. Resuscitation. Published 15 December 2023. doi:10.1016/j.resuscitation.2023.110095

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