Protection of the nasotracheal tube tip with a red rubber catheter in adults undergoing nasotracheal intubation: A randomized controlled trial
Primary resultResult — go to the resultOdds ratio 0.380 95 % CI 0.174–0.831Authors' conclusion
Use of the RRC significantly reduced the likelihood and severity of epistaxis following nasal intubation, at the cost of longer time to intubation.
Study context
- Population
- Adults undergoing surgery requiring nasotracheal intubationrandomized 1:1
- Participants
- 112 adults
- Comparison
- Thermosoftened, lubricated nasotracheal tube (NTT) telescoped into RRC vs NTT alone
- Primary endpoint
- Incidence of epistaxis assessed by a blinded observer
- Follow-up
- 5 min post-intubation
Methodological detailstwo-center, single-blinded
- Two-center
- Single-blinded
Primary result
As reported in the abstract
Odds ratio
0.380
95 % CI 0.174–0.831
P = 0.0153
By group
RRC vs NTT alone
OR 0.380 (95 % CI 0.174–0.831); P = 0.0153
Secondary outcomes
| Outcome | OR for lower severity (95 % CI) | P value | |
|---|---|---|---|
| Severity of epistaxisFDR = 0.0013 | 4.145 (1.923–8.934) | P = 0.0003 | |
| 0.10.31310OR for lower severity (log scale) |
Time to intubation · FDR = 0.0015, d = 0.70
P = 0.0005
Postoperative pain in PACU
- No difference in postoperative pain
Safety
Procedural complications during nasotracheal intubation (NTI)
- No difference in the rate of procedural complications
Original publication
Protection of the nasotracheal tube tip with a red rubber catheter in adults undergoing nasotracheal intubation: A randomized controlled trial. J Clin Anesth. Published 24 December 2025. doi:10.
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