Perioperative medicine & outcomes
Psychological Effects of Explicit Recall under Sedation and after Surgery (PEERS): A Prospective Cohort Study on 2,500 Patients
Authors' conclusion
Explicit recall per se during sedation/regional anesthesia did not increase the odds of developing psychiatric illness.
Study context
- Population
- Adults undergoing elective total hip or knee arthroplasty under sedation/RA, University Hospital, London, Ontario, Canada, September 2021 to March 20242,138 analysed
- Participants
- 2,500 adults
- Exposure
- Explicit recall vs no explicit recall under sedation/RA
- Explicit recalln = 475
- Outcome
- Co-primary: probable depression (Patient Health Questionnaire score ≥8) and suspected PTSD symptoms (PTSD Checklist for Civilians score ≥13)
- Follow-up
- 6 weeks postoperatively
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Association of explicit recall with co-primary outcomes
Explicit recall
22.2%
475
Observational data: associations, not effects.
Further findings
Psychological effects of surgery, entire cohort · postoperatively
- New probable depression
- 61 (5%)
- Suspected posttraumatic stress disorder (PTSD)
- 105 (5%)
- New suicidal ideation
- 95 (4.4%)
- New psychiatric consultation required (estimated)
- 1 in 18
Original publication
Psychological Effects of Explicit Recall under Sedation and after Surgery (PEERS): A Prospective Cohort Study on 2,500 Patients. Anesthesiology. Published 9 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →