Transitioning from intrathecal bupivacaine to mepivacaine for same-day discharge total joint arthroplasty: a quality improvement study
Authors' conclusion
Intrathecal mepivacaine was associated with increased perioperative OMME consumption and PACU pain scores, but still realized a decreased PACU length of stay.
Study context
- Population
- Same-day discharge total knee and hip arthroplasty under subarachnoid block, academic quaternary centre, September 20 to December 20, 2021knee and hip arthroplasties
- Participants
- 96 participants
- Exposure
- Intrathecal isobaric mepivacaine vs hyperbaric bupivacaine
- Outcome
- Time to discharge from postanesthesia care unit (PACU)
Methodological detailssingle surgeon, before-after
- Single surgeon
- Before-after
Main finding
As reported in the abstract
PACU LOS
P = 0.008
Observational data: associations, not effects.
Further findings
Perioperative oral MME
P < 0.001
Mean
| Outcome | Mepivacaine | Bupivacaine | P value |
|---|---|---|---|
| PACU pain scores | 6.29 | 3.41 | P < 0.01 |
Conversion to general anesthesia (GA) or overnight admission
- No difference in conversion to GA or overnight admission
Original publication
Transitioning from intrathecal bupivacaine to mepivacaine for same-day discharge total joint arthroplasty: a quality improvement study. Reg Anesth Pain Med. Published 11 July 2023. doi:10.
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