The anesthetic and recovery profiles of low-dose hypobaric mepivacaine and bupivacaine for spinal anesthesia in total hip and knee arthroplasty: a prospective observational study
Authors' conclusion
The anesthetic profiles of low-dose hypobaric mepivacaine and bupivacaine were favorable for fast-track hip and knee arthroplasty with short and predictable operating times.
Study context
- Population
- Patients undergoing hip and knee arthroplasty
- Participants
- 30 vs 30
- Exposure
- Low-dose hypobaric mepivacaine vs bupivacaine for spinal anaesthesia
- Mepivacainen = 30
- Bupivacainen = 30
- Outcome
- Time to sensory blockade at or above L1 / T10 in the operative limb
Main finding
As reported in the abstract
| Group | Value | T10 |
|---|---|---|
| Mepivacaine | mean 5.7 (SD 1.8) min | 7.3 (3.3) min |
| Bupivacaine | mean 6.2 (SD 2.6) min | 8.1 (4.8) min |
Value
Mepivacainemean 5.7 (SD 1.8) min
Bupivacainemean 6.2 (SD 2.6) min
T10
Mepivacaine7.3 (3.3) min
Bupivacaine8.1 (4.8) min
- Patients requiring anesthetic supplementation for surgical completion
- 4
Observational data: associations, not effects.
Further findings
Sensory block duration at or above T10 / L1 in the operative limb
L1 Mepivacaine 115 (37) min · Bupivacaine 161 (34) min
Time to return of motor function
- Sensory block duration at or above T10 / L1 in the operative limb: value = T10
Original publication
The anesthetic and recovery profiles of low-dose hypobaric mepivacaine and bupivacaine for spinal anesthesia in total hip and knee arthroplasty: a prospective observational study. Can J Anaesth. Published 10 December 2024. doi:10.
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