Pulmonary superinfection diagnosed with bronchoalveolar lavage at intubation in COVID patients: A Swedish single‐centre study
Authors' conclusion
One fourth of the patients with C-ARDS had a pulmonary superinfection in the lungs that was caused by another microorganism identified at intubation. Routine serum inflammatory markers could not be used to identify this complication. Microorganisms located in BAL at intubation were rarely associated with later VAP development.
Study context
- Population
- Patients with COVID-19 ARDS intubated in one Swedish county hospital intensive care unit (ICU) during the first pandemic yearBronchoalveolar lavage (BAL) specimens analysed
- Participants
- 112 patients
- Outcome
- Incidence of, and microorganisms responsible for, superinfection at first intubation (BAL fluid)
- Follow-up
- At intubation
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Pulmonary superinfection at intubation
Patients with superinfection
31
28%
Observational data: associations, not effects.
Further findings
Blood CRP, procalcitonin, neutrophils, lymphocytes
- Indistinguishable between patients with and without pulmonary superinfection
Ventilator-associated pneumonia (VAP) among patients on invasive mechanical ventilation (IMV) >48 h
- Treated with IMV >48 h
- 98 (88%)
- Diagnosed with VAP (of those on IMV >48 h)
- 37%
- Same bacterial strain at intubation superinfection and in VAP
- 1 patient
Original publication
Pulmonary superinfection diagnosed with bronchoalveolar lavage at intubation in COVID patients: A Swedish single‐centre study. Acta Anaesthesiol Scand. Published 28 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →