ICU sedation, delirium & recovery
Quality of life-related and non-quality of life-related issues in intensive care unit (ICU) survivors and non-ICU-treated controls: a multi-group exploratory factor analysis
Authors' conclusion
We found most issues experienced by ICU survivors to be unrelated to quality of life.
Study context
- Population
- Adult ICU survivors (ICU stay ≥72 h, 3 Swedish university hospital ICUs) and population controls
- Participants
- 395 vs 195
- Exposure
- ICU survivors vs non-ICU-treated controls matched for age and sex
- ICU survivorsn = 395
- Controlsn = 195reference
- Outcome
- Dimensionality of QoL perceptions: issues correlating to 13 domain-specific QoL questions (218-item, 13-domain provisional questionnaire)
- Follow-up
- 6 months to three years post-discharge
Methodological detailsmulti-group exploratory factor analysis, matched controls, multicentre, Analyses in Mplus with full information maximum likelihood for missing data; reliability by McDonald's omega or Cronbach's alpha
- Multi-group exploratory factor analysis
- Matched controls
- Multicentre
- Analyses in Mplus with full information maximum likelihood for missing data; reliability by McDonald's omega or Cronbach's alpha
Main finding
As reported in the abstract
Issues correlating to QoL
- All domains except Cognition had a subset of questions correlating to the domain-specific quality of life (QoL) question in at least the ICU survivor group
- Physical health, Sexual health and Gastrointestinal (GI) functions mainly correlated the same issues to QoL in both groups
- Fatigue, Pain, Mental health, activities of daily living, Sleep, Sensory functions and Work life showed considerable differences between groups
- Proportion of issues correlated to QoL: ICU survivors about one-fourth; controls about one-tenth
Observational data: associations, not effects.
Original publication
Quality of life-related and non-quality of life-related issues in ICU survivors and non-ICU-treated controls: a multi-group exploratory factor analysis. Crit Care. Published 29 March 2024. doi:10.
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