ICU sedation, delirium & recovery

The 1‐Year Functional Recovery From Severe COVID‐19 in a Swedish Working‐Age Cohort

Acta Anaesthesiol ScandPublished Retrospective cohort study

Authors' conclusion

This national cohort study, in ICU and hospitalized patients with COVID-19, shows that the severity of COVID-19 disease, functional and health status before COVID-19, and demographic factors had a major impact on recovery.

Study context

Population
Working-age individuals with COVID-19 admitted to intensive care unit (ICUs) or hospitals until July 20, 2020, Swedish national registries
Participants
1,020 / 5,306 / 4,387
Exposure
COVID-19 ICU patients vs COVID-19 hospital patients and matched population controls
  • ICUn = 1,020
  • Hospitaln = 5,306
  • Population controlsn = 4,387
Outcome
Sick leave-free days alive
Follow-up
First year after hospital discharge
Methodological detailsnational registries, matched population controls, adjusted for confounding (logistic regression)
  • National registries
  • Matched population controls
  • Adjusted for confounding (logistic regression)

Main finding

As reported in the abstract

For at least one more sick leave-free day alive; adjusted
Odds ratio (95% CI)P value
ICU vs Hospital
0.14(0.12–0.16)
P < 0.001
ICU vs Population controls
0.02(0.02–0.03)
P < 0.001

Observational data: associations, not effects.

Further findings

On sick leave · 1 year after inclusion

Similar but inverse ORs

Original publication

The 1‐Year Functional Recovery From Severe COVID‐19 in a Swedish Working‐Age Cohort. Acta Anaesthesiol Scand. Published 12 May 2025. doi:10.1111/aas.70058

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