Real-World Implications of Updated Surviving Sepsis Campaign Antibiotic Timing Recommendations*
Authors' conclusion
These data support recently updated SSC recommendations to align antibiotic timing targets with risk and probability stratifications.
Study context
- Population
- Adult hospitalized patients treated in the ED for suspected serious infection, 12 hospitals in the Southeastern US, 2017–2021
- Participants
- 166,559 participants · 12 hospitals
- Exposure
- Shock and infection-probability categories under updated Surviving Sepsis Campaign (SSC) antibiotic timing recommendations
- Outcome
- Number and characteristics of patients affected by updated SSC antibiotic initiation recommendations (time to antibiotics, mortality)
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Time to antibiotics and mortality by category
Time to antibiotics and mortality by category
Proportion of cohort Shock absent, possible infection 30%
Mortality Shock absent, possible infection 2% · Shock absent, probable infection 3% · Shock present, probable infection 17% · Shock present, possible infection 12%
Observational data: associations, not effects.
Original publication
Real-World Implications of Updated Surviving Sepsis Campaign Antibiotic Timing Recommendations*. Crit Care Med. Published 22 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →