Cardiac arrest & resuscitation

Recovery of arterial blood pressure after chest compression pauses in patients with out-of-hospital cardiac arrest

ResuscitationPublished Secondary analysis of the LUCAS 2 Active Decompression randomised trial

Authors' conclusion

ABP generated by mechanical CPR recovered quickly after pauses. Recovery of ABP after a pause was independent of pause duration.

Study context

Population
OHCA patients treated with mechanical chest compressions (LUCAS, 102 compressions/min) by an anesthesiologist-staffed rapid response car, Oslo, Norway (2015–2017), with arterial blood pressure (ABP) signal during cardiopulmonary resuscitation (CPR) and ≥1 compression pause >2 sec271 pauses
Participants
56 patients
Primary endpoint
Recovery of ABP (compression, mean, decompression) after compression pauses and its relationship with pause duration
Methodological detailsprospective
  • Prospective

Primary result

As reported in the abstract

Pause duration, median (Q1–Q3)
11 sec (7–18 sec)
Mean ABP, last pre-pause compression
53 ± 10 mmHg
Mean ABP during pause
33 ± 7 mmHg
Compression and mean ABP recovered to >90% of pre-pause pressure
within 2 compressions, or 1.7 sec
Pause duration did not affect ABP recovery post-pause (R2 compression, mean, decompression ABP)
0.05, 0.03, 0.01

Original publication

Recovery of arterial blood pressure after chest compression pauses in patients with out-of-hospital cardiac arrest. Resuscitation. Published 9 July 2024. doi:10.1016/j.resuscitation.2024.110311

Composed by AI from the published abstract and checked against it. How Briefs are made →

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