ICU sedation, delirium & recovery
Recovery of motor functions and cognitive functions in patients with intensive care unit–acquired weakness
Authors' conclusion
Cognitive function at ICU discharge and delirium duration significantly predicted ADL recovery.
Study context
- Population
- Patients with ICU-acquired weakness (ICU-AW) after ICU discharge
- Participants
- 65 patients
- Outcome
- ADL recovery
Methodological detailsData collected from ICU discharge to 4 weeks post-discharge
- Data collected from ICU discharge to 4 weeks post-discharge
Main finding
As reported in the abstract
Factors independently associated with ADL recovery (multivariable analysis)
Cognitive Functional Independence Measure (FIM) score at ICU discharge, β
19.12
p = 0.001
Delirium duration, β
−9.83
p < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Motor FIM gain, preserved cognition vs cognitive dysfunction (linear mixed model)Significant difference | P = 0.001 |
Cohort characteristics
- Age, median (IQR) years
- 61 (50-70)
- Females
- 44.6 %
- APACHE-II score, median (IQR)
- 25 (20-29)
- Surgical ICU patients
- 69.2 %
- Mechanical ventilation duration, median (IQR) days
- 19 (10-34)
- Delirium duration, median (IQR) days
- 3 (1-7)
Original publication
Recovery of motor functions and cognitive functions in patients with intensive care unit–acquired weakness. J Crit Care. Published 27 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →