Perioperative medicine & outcomes
Refining cardiovascular risk prediction after renal transplantation: a cross-sectional study focusing on NT-proBNP and the revised cardiac risk index
Main finding · Cardiovascular endpointsResult — go to the resultOdds ratio 9.6 CI 1.6–57.4Authors' conclusion
NT-proBNP alone could not predict 30-day CVE after KT.
Study context
- Population
- End-stage renal disease (ESRD) patients scheduled for kidney transplantation
- Participants
- 122 patients
- Exposure
- Pre-transplant NT-proBNP and revised cardiac risk index (RCRI) for predicting cardiovascular events (CVE) after kidney transplantation
- Outcome
- In-hospital and 1-month post-transplant CVEs
Methodological detailssingle-centre
- Single-centre
Main finding
Cardiovascular endpoints
Odds ratio
9.6
CI 1.6–57.4
RCRI = 3 vs RCRI 1 and 2
OR 9.6 (CI 1.6–57.4)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Baseline characteristics
- Median age (years)
- 47.7
- Pre-existing hypertension
- 80.3%
- Diabetes
- 26.2%
- Smoking history
- 9.0%
- Cardiovascular disease
- 23%
- RCRI score of 1
- 64.8%
NT-proBNP above 1200 pg/mL
- Over half of patients had NT-proBNP above 1200 pg/mL
- Higher NT-proBNP associated with lower left ventricular ejection fraction (LVEF) and higher systolic pulmonary artery pressure (PAP)
- RCRI not significantly different between NT-proBNP above vs below 1200 pg/mL
Original publication
Refining cardiovascular risk prediction after renal transplantation: a cross-sectional study focusing on NT-proBNP and the revised cardiac risk index. Perioper Med (Lond). Published 21 October 2025. doi:10.
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