Cardiac arrest & resuscitation
The relationship between cardiopulmonary resuscitation duration and prognosis in patients with out-of-hospital cardiac arrest due to asphyxiation
Main finding · One-month survivalResult — go to the resultAdjusted odds ratio per minute 0.88 95% CI 0.86–0.90Authors' conclusion
Prolonged CPR was associated with poor outcomes in patients with asphyxiation-related OHCA and may be futile in these cases.
Study context
- Population
- Adults with asphyxial out-of-hospital cardiac arrest (OHCA) who received EMS cardiopulmonary resuscitation (CPR) and achieved return of spontaneous circulation, Japanese Association for Acute Medicine OHCA registry, June 2014 to December 2021
- Participants
- 2,594 adults
- Exposure
- CPR duration
- Outcome
- One-month survival
- Follow-up
- One month
Methodological detailsregistry-based, multivariable logistic regression
- Registry-based
- Multivariable logistic regression
Main finding
As reported in the abstract
Adjusted odds ratio per minute
0.88
95% CI 0.86–0.90
CPR duration (per minute)
aOR per minute 0.88 (95% CI 0.86–0.90)
Per minute, as printed
- Survived at one month
- 515 patients (19.9%)
- Probability of survival dropped below 1% after CPR of
- 31 min
- Median CPR duration (IQR 17-35 min)
- 26 min
Observational data: associations, not effects.
Secondary outcomes
| Outcome | aOR per minute (95% CI) | |
|---|---|---|
| Favourable neurological outcome (CPC 1 or 2) · one month | 0.78 (0.71–0.85) | |
| 0.512Adjusted odds ratio per minute (log scale) |
- Favourable neurological outcome (CPC 1 or 2) — Favourable neurological outcome at one month
- 62 (2.4%)
- Favourable neurological outcome (CPC 1 or 2) — Probability dropped below 1% after CPR of
- 4 min
Original publication
The relationship between cardiopulmonary resuscitation duration and prognosis in patients with out-of-hospital cardiac arrest due to asphyxiation. Resuscitation. Published 11 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →