Perioperative medicine & outcomes
Relationship between perioperative anaphylaxis and history of allergies or allergic diseases: A systematic review and meta-analysis with meta-regression
Authors' conclusion
Patients with previous drug allergies, food allergies, a history of allergies, or atopy are more likely to develop anaphylaxis during the perioperative period.
Study context
- Population
- Patients undergoing the perioperative period (perioperative anaphylaxis)19 studies
- Comparison
- History of allergies/allergic diseases vs none
- Outcome
- Perioperative anaphylaxis
Methodological detailsmeta-regression, subgroup analysis, sensitivity analysis, 2 investigators independently searched, screened and collected data (MEDLINE, EMBASE, Cochrane CENTRAL)
- Meta-regression
- Subgroup analysis
- Sensitivity analysis
- 2 investigators independently searched, screened and collected data (MEDLINE, EMBASE, Cochrane CENTRAL)
Pooled result
As reported in the abstract
Incidence of perioperative anaphylaxis
Odds ratio (95% CI)
Drug allergies
3.54(1.07–11.69)
Food allergies
2.29(1.23–4.26)
A history of allergies
4.86(3.65–6.49)
Atopy
3.58(1.47–8.71)
Further pooled results
- History of allergies/allergic diseases did not increase the presence of immune-mediated reactions or the severity of perioperative anaphylaxis
Original publication
Relationship between perioperative anaphylaxis and history of allergies or allergic diseases: A systematic review and meta-analysis with meta-regression. J Clin Anesth. Published 22 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →