Obstetric anesthesia

Remimazolam use in obstetric patients: a single-center retrospective study (2021–2024)

Int J Obstet AnesthPublished Scoping review

An erratum to this article was published (Int J Obstet Anesth, Aug 2026 ↗)

Authors' conclusion

While preliminary findings are encouraging, the current evidence is limited by the small cohorts evaluated in studies.

Study context

Population
Obstetric patients receiving remimazolam (labour analgesia, caesarean delivery, termination of pregnancy, procedural sedation during obstetric care)case reports, case series, RCTs
Outcome
Remimazolam use in obstetric anaesthesia
Methodological detailsno restrictions on study design or manuscript type, grey literature and non-peer-reviewed sources excluded, PubMed and Ovid searched, inception to April 1, 2025, English-language manuscripts
  • No restrictions on study design or manuscript type
  • Grey literature and non-peer-reviewed sources excluded
  • PubMed and Ovid searched, inception to April 1, 2025, English-language manuscripts

Main finding

As reported in the abstract

  • Remimazolam may be safely used in high-risk obstetric populations including those with maternal cardiac disease, providing effective sedation, stable haemodynamics, high patient satisfaction and favourable maternal-fetal outcomes
  • Availability of flumazenil as a reversal agent adds a safety margin
  • Literature primarily case reports, case series and RCTs (counts not printed)

Original publication

Remimazolam use in obstetric patients: a single-center retrospective study (2021–2024). Int J Obstet Anesth. Published 8 August 2025. doi:10.1016/j.ijoa.2025.104750

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