Repeat dose steroid in high pain responders after total knee arthroplasty: A study protocol
Study context
- Population
- High pain catastrophizers (Pain Catastrophizing Scale > 20) with moderate to severe pain (VAS > 30) during a 5 m walk test 24 h after total knee arthroplasty (TKA), having received preoperative dexamethasone (1 mg/kg)planned
- Participants
- 55 vs 55
- Planned comparison
- Repeat oral dexamethasone 24 mg vs placebo on evening of Day 1 after TKA
- Dexamethasonen = 55
- Placebon = 55reference
- Primary endpoint
- Moderate to severe pain (VAS > 30) during a 5 m walk test
- Follow-up
- Morning of Day 2 after surgery
Methodological detailsplacebo-controlled, Pain diary for 7 days after surgery, Follow-up at 8 and 30 days
- Placebo-controlled
- Pain diary for 7 days after surgery
- Follow-up at 8 and 30 days
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Repeat dose steroid in high pain responders after total knee arthroplasty: A study protocol. Acta Anaesthesiol Scand. Published 1 February 2023. doi:10.
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