ICU sedation, delirium & recovery

Resilience after severe critical illness: a prospective, multicentre, observational study (RESIREA)

Crit CarePublished Prospective observational cohort study

Authors' conclusion

Resilient patients had a lower prevalence of PTSD symptoms and higher quality of life scores, compared to patients with low resilience. Higher scores for social support and illness perception were independently associated with greater resilience.

Study context

Population
ICU survivors given mechanical ventilation and vasoactive amines for shock, 41 French ICUs, assessed 3 months to 1 year after ICU admission
Participants
382 participants · 41 French ICUs
Exposure
Normal or high resilience vs low resilience
  • Resilientn = 203
Outcome
Resilience (CD-RISC-25) and its associations with post-traumatic stress disorder (PTSD) symptoms (IES-R) and quality of life (SF-36)
Follow-up
Three months to one year after ICU admission
Methodological detailsmulticentre, conducted in parallel with the NUTRIREA-3 trial
  • Multicentre
  • Conducted in parallel with the NUTRIREA-3 trial

Main finding

As reported in the abstract

Moderate to severe PTSD symptoms (IES-R ≥ 24)

P = 0.002

Normal or high resilience (Connor-Davidson Resilience Scale (CD-RISC-25) ≥ 68)
203 (53.1%)

Observational data: associations, not effects.

Further findings

Quality of life (SF-36)

Resilient patients had higher SF-36 scores

Factors independently associated with higher CD-RISC-25 scores

Higher Multidimensional Scale of Perceived Social Support (MSPSS) score (stronger social support): OR 1.027, 95%CI 1.008-1.047
P = 0.005
Lower Brief Illness Perception Questionnaire (B-IPQ) scores (more threatening illness perception): OR 0.973, 95%CI 0.950-0.996
P = 0.02

Original publication

Resilience after severe critical illness: a prospective, multicentre, observational study (RESIREA). Crit Care. Published 12 July 2024. doi:10.1186/s13054-024-04989-x

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