ICU sedation, delirium & recovery
Mechanisms underlying neurocognitive dysfunction following critical illness: a systematic review
Authors' conclusion
The underlying pathophysiology of neurocognitive decline after critical illness is not yet understood fully.
Study context
- Population
- Adults with critical illness of any aetiology assessed for cognitive impairment after recovery
- Participants
- 4,344 adults · 37 studies
- Outcome
- Mechanisms underlying neurocognitive dysfunction after critical illness
Methodological detailsNewcastle-Ottawa scale quality assessment, Most studies single-centre with < 100 patients, Literature searched 1 January 1974 to 15 July 2023; 7658 references reviewed
- Newcastle-Ottawa scale quality assessment
- Most studies single-centre with < 100 patients
- Literature searched 1 January 1974 to 15 July 2023; 7658 references reviewed
Pooled result
As reported in the abstract
Proportion of patients with long-term cognitive impairment
13% to 100%
Original publication
Mechanisms underlying neurocognitive dysfunction following critical illness: a systematic review. Anaesthesia. Published 12 December 2024. doi:10.
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