Cardiac arrest & resuscitation
Restrictive versus high-dose oxygenation strategy in post-arrest management following adult non-traumatic cardiac arrest: a meta-analysis
Pooled result · Short-term survival (≤ 90 days)Result — go to the resultRR for short-term survival 0.99 95% CI 0.90–1.10Authors' conclusion
Restrictive and high-dose oxygenation strategy following CA did not result in differences in short-term or in-hospital survival.
Study context
- Population
- Adult survivors of non-traumatic cardiac arrest, post-ROSC management
- Participants
- 1,941 survivors · 8 randomized controlled trials (RCTs)
- Comparison
- Restrictive vs high-dose oxygenation strategy after return of spontaneous circulation (ROSC)
- Restrictiven = 964
- High-dosen = 977reference
- Outcome
- Short-term survival
- Follow-up
- ≤ 90 days
Methodological detailsprospectively registered
- Prospectively registered
Pooled result
Short-term survival (≤ 90 days)
RR for short-term survival
0.99
95% CI 0.90–1.10
P = 0.90
By group
Restrictive vs High-dose
RR for short-term survival 0.99 (95% CI 0.90–1.10); P = 0.90
As reported in the abstract
Further pooled results
Survival to hospital discharge
- No evidence for a difference
Safety
| Outcome | RR (95% CI) | P value | |
|---|---|---|---|
| Episodes of hypoxemia4 trials, I2 = 13% | 2.06 (1.47–2.89) | P = 0.004 | |
| 0.20.5125Relative risk (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Restrictive versus high-dose oxygenation strategy in post-arrest management following adult non-traumatic cardiac arrest: a meta-analysis. Crit Care. Published 5 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →