Organ support & nutrition

Right ventricular injury in patients with COVID-19-related acute respiratory distress syndrome (ARDS) eligible for extracorporeal membrane oxygenation (ECMO) support: a multicenter retrospective study

Ann Intensive CarePublished Retrospective cohort study

Main finding · 90-day mortalityResult — go to the resultHazard ratio 1.92 CI 1.10–3.37

Authors' conclusion

Among COVID-19-associated ARDS patients who met the EOLIA criteria, those with significant RV pressure overload had a particularly poor outcome.

Study context

Population
Patients with confirmed SARS-CoV-2 infection and ARDS with available echocardiography, 3 French intensive care units (ICUs) of teaching hospitals, March 2020–March 202118 on ECMO excluded
Participants
283 patients
Exposure
EOLIA + RV injury (RVI) + vs EOLIA + RVI - vs EOLIA -
  • EOLIA -n = 107reference
  • EOLIA + RVI -n = 126
  • EOLIA + RVI +n = 32
Outcome
Mortality
Follow-up
90 days
Methodological detailsobservational, multicentre
  • Observational
  • Multicentre

Main finding

90-day mortality

Hazard ratio

1.92

CI 1.10–3.37

By group

RVI
HR 1.92 (CI 1.10–3.37)

As reported in the abstract

Observational data: associations, not effects.

Further findings

Patients who received ECMO
18 (6.3%)

Original publication

Right ventricular injury in patients with COVID-19-related ARDS eligible for ECMO support: a multicenter retrospective study. Ann Intensive Care. Published 26 March 2024. doi:10.1186/s13613-024-01256-8

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