Risk factors for peripartum anemia and blood transfusion: a two-center retrospective cohort study (2018–2020)
Authors' conclusion
Anemia was more common among socioeconomically disadvantaged and non-Hispanic Black patients. Transfusion was associated with site, clinical factors, and anemia severity.
Study context
- Population
- Singleton deliveries ≥28 weeks with third-trimester Hb values at two Chicago hospitals (March 1, 2018 - February 29, 2020)
- Participants
- 31,979 deliveries
- Outcome
- Third trimester anemia (Hb <11 g/dL)
Methodological detailstwo-centre
- Two-centre
Main finding
As reported in the abstract
Third-trimester anemia
Third-trimester anemia prevalence (12,841 patients)
40.2%
Anemia in non-Hispanic Black patients
53.3%
Anemia associated with age, adjusted RR per year
0.99
Anemia associated with delivery at University of Chicago, adjusted RR
1.92
Observational data: associations, not effects.
Secondary outcomes
Peripartum transfusion
- Hispanic ethnicity, adjusted OR
- 1.62
- Asian race, adjusted OR
- 1.42
- Non-Hispanic Black race not associated, adjusted OR
- 1.10
- Transfusions more frequent at Northwestern
- Transfusion associated with anemia severity and cesarean delivery
- Logistic regression, adjusted odds
Original publication
Risk factors for peripartum anemia and blood transfusion: a two-center retrospective cohort study (2018–2020). Int J Obstet Anesth. Published 24 August 2026. doi:10. 1016/ j. ijoa. 2026. 105269
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