Risk factors for persistent pain after breast cancer surgery: a multicentre prospective cohort study
Study context
- Population
- Asian and American women undergoing elective breast cancer surgery at KK Women's and Children's Hospital and Duke University Medical Center
- Participants
- 210 participants
- Outcome
- Persistent pain (pain score ≥ 3 or pain affecting activities of daily living)
- Follow-up
- 4 months after surgery
Methodological detailsmulticentre, predictive model development
- Multicentre
- Predictive model development
Main finding
As reported in the abstract
Persistent pain incidence and independent risk factors (multivariable model)
- Persistent pain
- 135 (64.3%)
- Multivariable model AUC
- 0.807
- Age, OR (95% CI) per 5 years
- 0.85 (0.74-0.98)
- Diabetes, OR
- 4.68 (1.03-21.22) (95% CI)
- Pre-operative pain score at sites other than the breast, OR
- 1.48 (1.11-1.96) (95% CI)
- Previous mastitis, OR
- 4.90 (1.31-18.34) (95% CI)
- Perceived stress scale, OR (95% CI) per 5 points
- 1.35 (1.01-1.80)
Observational data: associations, not effects.
Original publication
Risk factors for persistent pain after breast cancer surgery: a multicentre prospective cohort study. Anaesthesia. Published 13 January 2023. doi:10.
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