Risk factors for recurrence of post-dural puncture headache following an epidural blood patch: a retrospective cohort study
Authors' conclusion
Persistence of PDPH following a first EBP is not unusual.
Study context
- Population
- Obstetric patients with post-dural puncture headache (PDPH) requiring an epidural blood patch after a neuraxial procedure, large maternity hospital in Switzerland, 2001–2018required an epidural blood patch (EBP)
- Participants
- 212 patients
- Exposure
- Failed vs successful EBP
- Failed EBPn = 55
- Outcome
- Risk factors for EBP failure (absence of full symptom relief and need for further treatment)
Methodological detailssingle-centre, multivariate analysis
- Single-centre
- Multivariate analysis
Main finding
As reported in the abstract
EBP failure
Failed EBP
25.9%
55
Odds ratio (95% CI)
Epidural space deeper than 5.5 cm
3.08(1.26–7.49)
Interval dural puncture to EBP >48 h
0.20(0.05–0.83)
Observational data: associations, not effects.
Further findings
Signs and symptoms of PDPH
- Did not differ between groups
Original publication
Risk factors for recurrence of post-dural puncture headache following an epidural blood patch: a retrospective cohort study. Int J Obstet Anesth. Published 15 September 2023. doi:10.
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