Respiratory failure & ventilation
Role of age as eligibility criterion for ECMO in patients with ARDS: meta-regression analysis
Authors' conclusion
The relationship between age and ICU mortality is linear and shows no inflection point.
Study context
- Population
- ARDS patients treated with V–V ECMO (studies with ≥6 patients, 2015–June 2024)two cohorts: 173 and 103 studies
- Participants
- 56,257 vs 21,255
- Comparison
- Non-COVID ARDS vs COVID-19 ARDS
- Non-COVID ARDSn = 56,257
- COVID-19 ARDSn = 21,255
- Outcome
- Association of mean age with ICU and/or hospital mortality
Methodological detailsCOVID-19 and non-COVID-19 populations analysed separately, covariate-adjusted meta-regression
- COVID-19 and non-COVID-19 populations analysed separately
- Covariate-adjusted meta-regression
Pooled result
As reported in the abstract
ICU/hospital mortality vs mean age
Further pooled results
Sensitivity analyses
- Confirmed findings; linear relationship between age and mortality in both groups
Original publication
Role of age as eligibility criterion for ECMO in patients with ARDS: meta-regression analysis. Crit Care. Published 27 August 2024. doi:10.
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