Cardiac arrest & resuscitation
Role of EEG spindle-like activity in post cardiac arrest prognostication
Authors' conclusion
Spindle-like EEG activity may orient on prognostication of favorable outcome in adult post CA patients, and correlates with lower neuronal damage.
Study context
- Population
- Comatose adults after cardiac arrest (CA), institutional registry 09.2021–09.2023
- Participants
- 276 adults
- Exposure
- Spindle-like EEG activity vs no spindle-like activity
- Spindle-like activityn = 66
- Outcome
- Favorable outcome (CPC 1-2)
- Follow-up
- 3 months
Methodological detailsprospective institutional registry, single-centre
- Prospective institutional registry
- Single-centre
Main finding
As reported in the abstract
Prediction of CPC 1-2 by spindle-like activity within 72 h
| Group | Specificity | Sensitivity |
|---|---|---|
| Spindle-like activity | 82.2 % | 36.8 % |
Spindle-like activity
Specificity82.2 %
Sensitivity36.8 %
Observational data: associations, not effects.
Further findings
Peak serum NSE at 24-48 h
P < 0.001
Sensitivity of modified benign EEG with addition of spindle-like activity
- Sensitivity increased from 90.5 % to 95.8 % (p < 0.001); specificity 54.4 %
Original publication
Role of EEG spindle-like activity in post cardiac arrest prognostication. Resuscitation. Published 18 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →