Severe hemoptysis associated with lung cancer in the intensive care unit (ICU): recurrence and outcome
Authors' conclusion
Lung cancer-related SH is associated with a high rate of bleeding recurrence and a poor prognosis.
Study context
- Population
- ICU patients with severe hemoptysis associated with lung cancer requiring vascular interventional radiology, 2009–2020analysed
- Participants
- 130 patients
- Outcome
- Bleeding recurrence and its prognostic significance
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Bleeding recurrence
Bleeding recurrence
34%
Time to recurrence after initial vascular interventional radiology (VIR), days (median [IQR])
1
1–3
IV terlipressin prior to VIR associated with recurrence, OR (independent)
4.43
p = 0.001
Microbiologically documented lower respiratory tract infection (LRTI) associated with recurrence, OR (independent)
2.93
p = 0.007
Observational data: associations, not effects.
Further findings
Overall mortality · 28 days, 6 months, 12 months
- 28-day mortality
- 25.3%
- 6-month mortality
- 47.7%
- 12-month mortality
- 63%
Factors independently associated with 1-year mortality
- Tumoral cavitation, HR
- 3.37; p = 0.004
- Staphylococcus aureus infection, HR
- 8.3; p = 0.005
- Bleeding recurrence, HR
- 2.68; p = 0.01
Original publication
Severe hemoptysis associated with lung cancer in the ICU: recurrence and outcome. Ann Intensive Care. Published 20 March 2025. doi:10.
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