Sex-related Incidence of Stroke After Left Ventricular Assist Device Implantation: A Systematic Review and Meta-analysis
Pooled resultResult — go to the resultRelative risk 1.12 95% CI 1.04–1.21Authors' conclusion
Females demonstrate a significantly greater likelihood of experiencing post-LVAD stroke than males, especially in Asians.
Study context
- Population
- Adults with left ventricular assist devices (LVADs)
- Participants
- 47,125 adults · 28 studies
- Comparison
- Females vs males
- Outcome
- Post-LVAD implantation stroke
Methodological detailssubgroup analysis, meta-regression
- Subgroup analysis
- Meta-regression
Pooled result
As reported in the abstract
Relative risk
1.12
95% CI 1.04–1.21
Females vs Males
RR 1.12 (95% CI 1.04–1.21)
Further pooled results
| Outcome | RR (95% CI) | |
|---|---|---|
| Stroke (subgroup: Asian) | 1.40 (1.11–1.76) | |
| Stroke (subgroup: North American) | 1.25 (1.07–1.46) | |
| 0.512Relative risk (log scale) |
Meta-regression of RR on average age and publication year
- No significant relationship with average age
- P = 0.469
- No significant relationship with publication year
- P = 0.096
Original publication
Sex-related Incidence of Stroke After Left Ventricular Assist Device Implantation: A Systematic Review and Meta-analysis. J Cardiothorac Vasc Anesth. Published 22 September 2025. doi:10.
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