Shock index as predictor of massive transfusion and mortality in patients with trauma: a systematic review and meta-analysis
Authors' conclusion
Our study demonstrated that SI may have a limited role as the sole tool to predict the need for MT in adult trauma patients. SI is not accurate to predict mortality but may have a role to identify patients with a low risk of mortality.
Study context
- Population
- Adult patients with trauma
- Participants
- 670,728 patients · 35 studies
- Outcome
- Accuracy of SI to predict the need for massive transfusion (MT)
Methodological detailsPRISMA, QUADAS-2 risk of bias, Search of MEDLINE, Scopus, Web of Science from inception to March 2022
- PRISMA
- QUADAS-2 risk of bias
- Search of MEDLINE, Scopus, Web of Science from inception to March 2022
Pooled result
As reported in the abstract
MT prediction
| Group | Sensitivity | Specificity | AUC | LR+ | LR- |
|---|---|---|---|---|---|
| SI | 0.68 [0.57; 0.76] | 0.84 [0.79; 0.88] | 0.85 [0.81; 0.88] | 4.24 [3.18-5.65] | 0.39 [0.29-0.52] |
SI
Sensitivity0.68 [0.57; 0.76]
Specificity0.84 [0.79; 0.88]
AUC0.85 [0.81; 0.88]
LR+4.24 [3.18-5.65]
LR-0.39 [0.29-0.52]
Further pooled results
| Outcome | Values |
|---|---|
| Mortality prediction | SI sensitivity 0.358 [0.238; 0.498] · specificity 0.742 [0.656; 0.813] · AUC 0.553 · LR+ 1.39 [1.36-1.42] · LR- 0.87 [0.85-0.89] |
- Mortality prediction: AUC confidence region for sensitivity given specificity: [0.4014; 0.6759]; for specificity given sensitivity: [0.4799; 0.6332]
Original publication
Shock index as predictor of massive transfusion and mortality in patients with trauma: a systematic review and meta-analysis. Crit Care. Published 5 March 2023. doi:10.
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