Pediatric anesthesia & critical care
Short-term outcomes of asphyxiated neonates depending on requirement for transfer in the first 24 h of life
Main finding · In-hospital deathResult — go to the resultAdjusted odds ratio 4.08 95% CI 3.41–4.89Authors' conclusion
This comprehensive nationwide study found increased odds for adverse outcomes in neonates with BA who were transferred to another facility within 24 h of hospital admission.
Study context
- Population
- Full-term neonates with birth asphyxia admitted to a pediatric department on their first day of life, German hospitals, 2016–2021
- Participants
- 25,914 neonates
- Exposure
- Postnatal transfer within 24 h vs no transfer
- Outcome
- In-hospital death
Methodological detailsnationwide, hierarchical multilevel logistic regression
- Nationwide
- Hierarchical multilevel logistic regression
Main finding
As reported in the abstract
Adjusted odds ratio
4.08
95% CI 3.41–4.89
TN vs NTN
adjusted OR 4.08 (95% CI 3.41–4.89)
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Adjusted OR | |
|---|---|---|
| Seizures | 2.99 (95% CI 2.65–3.38) | |
| PCCC ≥ 2 | 1.76 (95% CI 1.52–2.05) | |
| Death, seizures and PCCC ≥ 2 in infants receiving TH (subgroup)TN vs NTN · death | 1.67 (CI 1.29–2.17) | |
| Death, seizures and PCCC ≥ 2 in infants receiving TH (subgroup)TN vs NTN · seizures | 1.26 (CI 1.07–1.48) | |
| Death, seizures and PCCC ≥ 2 in infants receiving TH (subgroup)TN vs NTN · PCCC ≥ 2 | 0.81 (CI 0.64–1.02) | |
| 0.20.5125Adjusted odds ratio (log scale) |
- Death, seizures and PCCC ≥ 2 in infants receiving therapeutic hypothermia (TH) (subgroup): TH subgroup n = 3,283
Original publication
Short-term outcomes of asphyxiated neonates depending on requirement for transfer in the first 24 h of life. Resuscitation. Published 11 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →