Pediatric anesthesia & critical care
Propofol and thiopental for intravenous induction in neonates: Study protocol for a dose‐finding trial
Study context
- Population
- Neonates from birth up to 28 postnatal days undergoing GA for surgical or diagnostic procedures, stratified by gestational and postnatal age
- Planned comparison
- Propofol vs thiopental for anesthesia induction
- Primary endpoint
- Median effective anesthetic induction dose of propofol and thiopental in neonates of different gestational and postnatal ages
Methodological detailssingle-center, prospective, open-label, interventional, Dixon's up-and-down method
- Single-center
- Prospective
- Open-label
- Interventional
- Dixon's up-and-down method
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Propofol and thiopental for intravenous induction in neonates: Study protocol for a dose‐finding trial. Acta Anaesthesiol Scand. Published 2 June 2023. doi:10.
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