Single-shot versus slow infusion interscalene block and its impact on diaphragmatic function in patients undergoing shoulder surgery, a double blind randomized controlled trial
Authors' conclusion
In adult patients undergoing arthroscopic shoulder surgery, slow infusion interscalene block reduced the incidence of complete phrenic nerve block to 7% compared to 83% in the single-shot block with comparable 24 h postoperative analgesic efficacy.
Study context
- Population
- Adults undergoing arthroscopic shoulder surgery83 analysed
- Participants
- 83 adults
- Comparison
- Slow infusion vs single-shot interscalene block
- Single shotn = 42reference
- Slow infusionn = 41
- Primary endpoint
- Incidence of complete phrenic nerve block
Methodological detailsdouble-blind
- Double-blind
Primary result
As reported in the abstract
Complete phrenic nerve block
Further findings
FEV1 and Forced Vital Capacity (FVC) · 30 min after block
- Significantly lower in the Single shot group
Resting NRS score and morphine consumption · 24 h
- Comparable between the groups
Original publication
Single-shot versus slow infusion interscalene block and its impact on diaphragmatic function in patients undergoing shoulder surgery, a double blind randomized controlled trial. Anaesth Crit Care Pain Med. Published 7 November 2025. doi:10.
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