Airway management

Sitting Versus Supine Modified Mallampati Test for Predicting Difficult Airway: A Systematic Review and Meta-analysis

Anesth AnalgPublished Systematic review and meta-analysis of observational studies

Authors' conclusion

The diagnostic accuracy of the modified Mallampati test for predicting difficult airway was not significantly associated with patient position.

Study context

Population
Patients assessed with the modified Mallampati test in both supine and sitting positions
Participants
8,261 patients · 20 studies
Comparison
Supine vs sitting modified Mallampati test
Outcome
Diagnostic accuracy for difficult laryngoscopy (Cormack-Lehane grade ≥III)
Methodological detailsbivariate random-effects models, meta-regression, paired design (same patients), Searched PubMed, Embase, Cochrane Database and Web of Science from inception to January 2026
  • Bivariate random-effects models
  • Meta-regression
  • Paired design (same patients)
  • Searched PubMed, Embase, Cochrane Database and Web of Science from inception to January 2026

Pooled result

As reported in the abstract

GroupPooled sensitivityPooled specificity
Sitting0.661 (95% CI, 0.573-0.738)0.783 (95% CI, 0.684-0.858)
Supine0.750 (95% CI, 0.617-0.849)0.705 (95% CI, 0.57-0.813)

Pooled sensitivity

Sitting0.661 (95% CI, 0.573-0.738)
Supine0.750 (95% CI, 0.617-0.849)

Pooled specificity

Sitting0.783 (95% CI, 0.684-0.858)
Supine0.705 (95% CI, 0.57-0.813)

Original publication

Sitting Versus Supine Modified Mallampati Test for Predicting Difficult Airway: A Systematic Review and Meta-analysis. Anesth Analg. Published 24 July 2026. doi:10.1213/ane.0000000000008235

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