Airway management

Sonometric assessment of cough predicts extubation failure: SonoWean—a proof-of-concept study

Crit CarePublished Prospective diagnostic accuracy study

Authors' conclusion

Sonometric assessment of cough strength might be helpful to identify patients at risk of extubation failure in patients undergoing IMV.

Study context

Population
Patients under invasive mechanical ventilation (IMV) >24 h completing a successful spontaneous T-tube SBT1-year period
Participants
106 participants
Comparison
Sonoscore in extubation failure vs success
  • Extubation failuren = 15
Outcome
Extubation failure prediction by Sonoscore (mean of 3-cough volume in decibels, sonometer, end of SBT)
Methodological detailsproof-of-concept
  • Proof-of-concept

Performance

As reported in the abstract

Sonoscore (mean 3-cough volume) and prediction of extubation failure

Sonoscore AUC (ROC) for extubation failure

0.91

95% CI 0.83–0.99P < 0.001

Sonoscore < 67.1 dB sensitivity

0.93

95% CI 0.70–0.99

Sonoscore < 67.1 dB specificity

0.82

95% CI 0.73–0.90

Further findings

Extubation failure rate

Extubation failure
15 (14%)

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Sonometric assessment of cough predicts extubation failure: SonoWean—a proof-of-concept study. Crit Care. Published 25 September 2023. doi:10.1186/s13054-023-04653-w

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