Paediatric anaesthesia & critical care
Standardized Perioperative Protocols and Variance in Pediatric Surgery
Authors' conclusion
In this study, the MViPS initiative was associated with reduced THC and LOS while maintaining outcomes.
Study context
- Population
- Pediatric surgery patients treated for protocol-specified conditions or procedures (typically <18 years), 2 academic pediatric tertiary referral centers in Oregon, October 2012 to November 2021
- Participants
- 1,081 patients · 2 centres
- Exposure
- Postprotocol vs preprotocol
- Postprotocoln = 519
- Preprotocoln = 562reference
- Outcome
- Length of stay (LOS), total hospital costs (THC), complications, and protocol compliance
Methodological detailspre-post (preprotocol vs postprotocol), multicentre (2 academic pediatric tertiary referral centers)
- Pre-post (preprotocol vs postprotocol)
- Multicentre (2 academic pediatric tertiary referral centers)
Main finding
As reported in the abstract
Study LOS and THC
Preprotocol vs PostprotocolIncidence rate ratio (95% CI)P value
Study LOS 23% shorter in postprotocol; estimated 191 hospital days reduction
1.23(1.11–1.38)
P < 0.001THC 10% lower in postprotocol; estimated reduction $266 709
1.10(1.01–1.20)
P = 0.03Observational data: associations, not effects.
Further findings
| Outcome | IRR (95% CI) | P value | |
|---|---|---|---|
| THCTHC 10% lower postprotocol; estimated reduction of $266 709 | 1.10 (1.01–1.20) | P = 0.03 | |
| 0.512Incidence rate ratio (log scale) |
Protocol compliance
- Protocol compliance
- 82% (426/519)
Complications
- Complication rates similar between groups
Extrapolation to patients treated per protocol since study end (up to April 2024)
- Patients
- 3167
- Estimated cost reduction
- $2 236 583
- Estimated hospital days reduction
- 1584
Original publication
Standardized Perioperative Protocols and Variance in Pediatric Surgery. JAMA Surg. Published 1 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →