Perioperative medicine & outcomes

Stellate ganglion block for preventing perioperative arrhythmias: a systematic review and meta-analysis

Br J AnaesthPublished Systematic review and meta-analysis of randomised controlled trials and observational studies

Pooled resultResult — go to the resultOdds ratio 0.22 95% CI 0.14–0.35

Authors' conclusion

Stellate ganglion block appears to reduce the incidence of perioperative arrhythmias in surgical patients.

Study context

Population
Adult surgical patients under GA
Participants
547 participants · 7 studies
Comparison
Stellate ganglion block (SGB) vs placebo, no intervention or alternative therapies
Outcome
Incidence of perioperative arrhythmias (intraoperative or postoperative atrial or ventricular arrhythmias, continuous ECG monitoring)
Methodological detailsGrading of Recommendations Assessment, Development and Evaluation (GRADE) certainty assessment
  • GRADE certainty assessment

Pooled result

As reported in the abstract

Odds ratio

0.22

95% CI 0.14–0.35

SGB vs Controls
OR 0.22 (95% CI 0.14–0.35)

Further pooled results

Perioperative arrhythmias by surgical type and arrhythmia subtype (subgroups)

Findings consistent across surgical types and arrhythmia subtypes

Safety

No serious adverse events related to SGB reported

Original publication

Stellate ganglion block for preventing perioperative arrhythmias: a systematic review and meta-analysis. Br J Anaesth. Published 17 December 2025. doi:10.1016/j.bja.2025.11.019

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