Cardiac arrest & resuscitation
Sub30: Feasibility study of a pre-hospital extracorporeal membrane oxygenation (ECMO) in patients with refractory out-of-hospital cardiac arrest in London, United Kingdom
Authors' conclusion
Whilst our study did not meet primary outcome of achieving full ECPR flow within 30-minute of collapse, it demonstrated safe, timely and effective delivery of ECPR with comparable survival rates by pre-hospital teams in a large metropolitan city
Study context
- Population
- Patients with refractory OHCA in London, UKcannulated for ECPR
- Participants
- 5 patients
- Outcome
- Established on pre-hospital ECPR within 30 min of the call to the emergency services
Methodological detailsopen-label, prospective, single-arm
- Open-label
- Prospective
- Single-arm
Main finding
As reported in the abstract
Established on pre-hospital ECPR within 30 min of call
Pre-hospital ECPR
0
events
Observational data: associations, not effects.
Further findings
Time from initial collapse to ECPR full flows
- ECPR full flows at a mean of 47 min (range 37-59 min) from initial collapse
Travel time to scene
- Median travel time to scene 14 min (range 3-20 min)
Survival to hospital discharge
- Survived to hospital discharge, of 5 patients (both CPC score 3; Modified Rankin Score (mRS) 4 and 5 respectively)
- 2
- Treatment withdrawn, of 5 patients
- 3
Original publication
Sub30: Feasibility study of a pre-hospital extracorporeal membrane oxygenation (ECMO) in patients with refractory out-of-hospital cardiac arrest in London, United Kingdom. Resuscitation. Published 5 December 2024. doi:10.
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