Cardiac arrest & resuscitation

The Minnesota Mobile Resuscitation Consortium ECMO truck: a feasibility study for extracorporeal cardiopulmonary resuscitation (ECPR) in refractory out-of-hospital cardiac arrest

ResuscitationPublished Retrospective cohort study

Authors' conclusion

A sustained, protocolized prehospital ECPR program using a purpose-built ECMO truck is feasible and achieves outcomes comparable to an established in-hospital ECPR system when matched on low-flow time.

Study context

Population
Adults (18–75 years) with refractory VF/VT out-of-hospital cardiac arrest (OHCA), Minnesota Mobile Resuscitation Consortiummatched cohort
Participants
8 vs 8
Exposure
ECMO truck vs Controls
  • ECMO truckn = 8
  • Controlsn = 8reference
Outcome
Survival to hospital discharge with favorable neurological status
Methodological detailssingle-center, prospectively collected registry, matched on low-flow time
  • Single-center
  • Prospectively collected registry
  • Matched on low-flow time

Main finding

As reported in the abstract

Neurologically favorable survival

P ≥ 0.99

Observational data: associations, not effects.

Further findings

Total low-flow time

P = 0.87

Needle-stick-to-ECMO flow time

P = 0.71

Baseline characteristics

Similar between groups

Original publication

The Minnesota Mobile Resuscitation Consortium ECMO truck: a feasibility study for ECPR in refractory out-of-hospital cardiac arrest. Resuscitation. Published 16 April 2026. doi:10.1016/j.resuscitation.2026.111089

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