Cardiac arrest & resuscitation

The FaciLItated hospital-based Extracorporeal Cardiopulmonary Resuscitation (ECPR) via Helicopter Transport (FLIGHT-to-ECPR) study

ResuscitationPublished Prospective observational cohort study

Authors' conclusion

A HEMS-facilitated, hospital-based ECPR strategy is feasible and safely expands rural access to advanced resuscitation while preserving neurologic outcomes comparable to standard ground-transport ECPR.

Study context

Population
Adults (18–75 years) with refractory VF/VT out-of-hospital cardiac arrest (OHCA) meeting Minnesota Mobile Resuscitation Consortium eligibility criteria, August 2021-December 202545 FLIGHT activations
Participants
27 vs 27
Exposure
Helicopter-EMS (HEMS)-facilitated hospital-based ECPR vs standard ground-transport ECPR
  • FLIGHTn = 27
  • Standard ground-transport ECPRn = 27reference
Outcome
Survival to discharge with favorable neurologic status (CPC 1-2)
Methodological detailssingle-center, matched cohort (1:1, matched on low-flow time)
  • Single-center
  • Matched cohort (1:1, matched on low-flow time)

Main finding

As reported in the abstract

Survival to discharge with favorable neurologic status (CPC 1-2), matched ECPR patients

Identical favorable neurologic survival in matched ECPR patients (n = 27/group)

25.9%

Observational data: associations, not effects.

Further findings

Favorable neurologic survival (CPC 1-2), all FLIGHT activations

Overall
33.3% (15/45)
Cannulated
25.9% (7/27)
Non-cannulated, achieving ROSC or meeting termination criteria
44.4% (8/18)

Low-flow time, matched ECPR patients

Similar low-flow times (mean ± SD, min)
85.9 ± 29.3 vs. 87.1 ± 29.2 min
  • p ≥ 0.99

Cannulation performance, ECMO duration, hospital LOS

No differences observed

Original publication

The FaciLItated hospital-based ECPR via Helicopter Transport (FLIGHT-to-ECPR) study. Resuscitation. Published 20 May 2026. doi:10.1016/j.resuscitation.2026.111137

Composed by AI from the published abstract and checked against it. How Briefs are made →

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